BIOSTATS 6016EX - Clinical Biostatistics

The aim of this course is to enable students to use correctly statistical methods of particular relevance to evidence-based health care and to advise clinicians on the application of these methods and interpretation of the results. The content includes: Clinical trials (equivalence trials, cross-over trials); Clinical agreement (Bland-Altman methods, kappa statistics, intraclass correlation); Statistical process control (special and common causes of variation; quality control charts); Diagnostic tests (sensitivity, specificity, ROC curves); Meta-analysis (systematic reviews, assessing heterogeneity, publication bias, estimating effects from randomized controlled trials, diagnostic tests and observational studies).